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Targeted Request for Proposals (RFP):
Exploring the mechanisms for HIV persistence and the potential for HIV eradication

Complete RFP available online at http://www.amfar.org/rfp

DEADLINE
Letters of Intent must be submitted no later than September 16, 2010

BACKGROUND
This RFP solicits proposals relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Highly active antiretroviral therapy (HAART) has significantly impacted the health of individuals infected with HIV-1. However, if therapy is interrupted, there is a rapid resumption of viral replication. Understanding the mechanisms by which the virus is able to persist in the face of therapy is necessary in order to identify strategies that may interrupt viral persistence and ultimately lead to viral eradication. amfAR wishes to support basic, clinical, and especially translational research exploring the mechanisms whereby HIV infection persists; the chronic nature of viral reservoirs and latency; and barriers to the eradication of HIV, with the potential goal of ultimately eliminating HIV infection.

AVAILABLE FUNDING AND PERFORMANCE PERIOD
Funding will be available for:

Research Grants - $100,000 direct costs plus up to 20% for indirect costs. The performance period for grants awarded under this RFP will be for one year starting March 1, 2011.

Fellowships - $110,000 direct costs and $3,636 for amfAR designated travel costs, plus up to 10% for indirect costs. The performance period for fellowships awarded under this RFP will be for two years starting March 1, 2011.

See the RFP posted at http://www.amfar.org/rfp for eligibility requirements and additional information.
 


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