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RFP: Gene Tx to Cure HIV: non-HIV and HIV scientists invited to apply


Funding up to 400K available to HIV & NON-HIV scientists for research on Gene Therapy to Cure HIV

CLICK HERE TO VIEW THE FULL REQUEST FOR PROPOSALS (RFP)

Deadlines
January 12, 2017, 3:00 PM: request log-in credentials
January 18, 2017, 3:00 PM: LOI submission

Overview
Several barriers to the development of safe and effective gene therapy treatments overlap across disease areas. Advances made in the context of any disease may inform the development of a gene therapy-based cure for HIV.

Purpose of RFP: Develop a gene therapy-based approach to curing HIV

Grant topics:

1 .Maximize in vivo transduction efficiency
OR
2. Optimize targeting effectiveness
OR
3. Achieve appropriate persistence of gene modifications
OR
4. Expand modified hematopoietic stem cells in vitro

Funding model
During the initial one-year funding period, grantees will compete to achieve the goals outlined in the grant topics. Those research teams that best reach the goal of each grant topic will be invited to submit a proposal for subsequent funding (ARCHE-GT), working with teams that have achieved the goals of other grant topics. ARCHE-GT grantees will be required to participate actively and cooperatively in regular conference calls and in-person meetings to share data and advance the program’s goals.

Expected outcomes
This initial one-year period of funding will be used to select research teams best suited to participate subsequently in ARCHE-GT, to be launched in 2018. The ARCHE-GT team will be expected to develop curative gene therapy product(s) that can be tested in clinical studies.

Available funding
In the initial one-year period, each grant is funded at up to $400,000 including indirect costs at a maximum 20% rate. The performance period begins on May 1, 2017, or later, and will end no later than April 30, 2018.

Eligibility
Researchers with doctoral degrees, with or without documented experience in HIV research, are eligible to apply.

Please share this announcement with colleagues (especially those with expertise in gene therapy) who may be interested in applying for this funding opportunity.

CLICK HERE FOR COMPLETE INFORMATION ABOUT THE RFP AND HOW TO APPLY
 
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