PhD Fellowship: Biomarker HIV associated TB

The South African Tuberculosis Vaccine Initiative performs cutting-edge clinical and immunology research in TB pathogenesis, diagnostic and prognostic biomarkers, and vaccine development. We are inviting applications for a PhD fellowship to take part in a project that will evaluate performance of a blood RNA biomarker of TB disease in HIV infected persons. This project (CORTIS-HR), funded by the Bill & Melinda Gates Foundation, is being conducted in collaboration with partners at Stellenbosch University, CAPRISA, and the Aurum Institute. The PhD student will be based at the University of Cape Town. The successful candidate will design and perform analytic approaches to evaluate the effects of demographic, clinical, and laboratory factors, including HIV treatment and viral suppression markers, on the diagnostic and prognostic performance of a blood-based RNA signature for TB disease that was discovered and validated in HIV uninfected persons. 

Key Requirements: 
  • MBChB or Masters degree in Public Health or related field. 
  • Epidemiology and Biostatistical experience. 
  • Proficiency in analysis of large datasets. 
  • Familiarity with R and/or Stata programming.